個(gè)人信息：

金郁

電子郵件：jiny@ecust.edu.cn

聯(lián)系電話：021-64250633

個(gè)人簡(jiǎn)介：

金郁：博士，副教授。遼寧省沈陽(yáng)人。2008年畢業(yè)于中國(guó)科學(xué)院大連化學(xué)物理研究所分析化學(xué)專業(yè)。本人主要從事復(fù)雜樣品的分離分析工作。根據(jù)復(fù)雜樣品分離純化中的難點(diǎn)問題，開展新型色譜固定相基本性能和潛在應(yīng)用的系統(tǒng)評(píng)價(jià)工作。以中藥系統(tǒng)分離與化學(xué)表征方法學(xué)研究為課題，重點(diǎn)開展了中藥系統(tǒng)分離的研究工作，發(fā)展了互補(bǔ)分離和目標(biāo)制備方法，建立了新型的線性放大技術(shù)和樣品濃縮技術(shù)。建立了中藥標(biāo)準(zhǔn)組分的標(biāo)準(zhǔn)化表征方法，解決化學(xué)表征過程中數(shù)據(jù)的可比性和通用性問題。發(fā)展了中藥類化合物的質(zhì)譜目標(biāo)篩選方法。近兩年，本人的研究重點(diǎn)放在復(fù)雜樣品中強(qiáng)極性化合物和微量化合物的分離表征工作，將利用以前的工作基礎(chǔ)，發(fā)展親水色譜，選擇性富集和正交分離這三個(gè)關(guān)鍵技術(shù)，并且形成以分離對(duì)象為中心的技術(shù)集成，以解決強(qiáng)極性化合物和微量化合物分離純化的難題。本人已承擔(dān)和參加了多個(gè)科研項(xiàng)目的研究工作，國(guó)家自然科學(xué)基金青年基金“寡糖的高效分離純化研究”，“重大新藥創(chuàng)制”科技重大專項(xiàng)“十一五”計(jì)劃項(xiàng)目“絡(luò)病理論指導(dǎo)藥物開發(fā)集成創(chuàng)新技術(shù)平臺(tái)建設(shè)” (2009ZX09313-003)。目前已在國(guó)外期刊上發(fā)表論文29篇，作為第一作者或者通訊作者14篇，影響因子大于3.0的15篇；國(guó)內(nèi)期刊上發(fā)表論文10篇；發(fā)表國(guó)際會(huì)議論文3篇；參加著作編寫2項(xiàng)；申請(qǐng)專利3項(xiàng)。

 

代表性文章

[1]  Qiaoxia Liu,^a Yanxiong Ke^a, Yu Jin^*a, Feifang Zhang^*a and Xinmiao Liang^a,b, Analysis of cephalosporins by hydrophilic interaction chromatography, Journal of Pharmaceutical and Biomedical Analysis, 2011, 54: 623-628

[2]  Jiatao Feng^a, Yuansheng Xiao^a, Zhimou Guo^a, Danhua Yu,^b Yu Jin^b*, Xinmiao Liang^{a, b *}_, Two-dimensional preparation of compounds from traditional Chinese medicine with Click oligo (ethylene glycol) column and C18 column, Journal of separation science, 2011, 34, 299-301

[3] Jia-tao Feng, Zhi-mou Guo, Hui Shi, Jiang-ping Gu, Yu Jin^*, Xin-miao Liang^*，Orthogonal separation on one beta-cyclodextrin column by switching reversed-phase liquid chromatography and hydrophilic interaction chromatography, talanta,2010,81:1870-1876

[4]  Yingyu Li, Peichun Dai, Yanxiong Ke^*, Yu Jin^*, Xinmiao Liang, Preparation of a stationary phase with s-triazine ring embedded group for reversed phase high-performance LC, Journal of separation science, 2010, 33: 2998-3004

[10] Mei-yun Xue, Hong-xue Huang, Yan-xiong Ke, Chang-hu Chu, Yu Jin*, Xin-miao Liang. “Click dipeptide”: A novel stationary phase applied in two-dimensional liquid chromatography. Journal of Chromatography A, 2009, 1216: 8623–8629.

[5] Yu Jin, Xing-ya Xue, Yan-fang Liu, Yuan-sheng Xiao, Jin Zhang, Hui Shi, Fei-fang Zhang, Xin-miao Liang ^*, A novel method of prediction and optimization for preparative high-performance liquid chromatography separation. Journal of Chromatography A, 2008, 1183: 76–86.

[6] Yu Jin, Tu Liang, Qing Fu, Yuan-sheng Xiao, Jia-tao Feng, Yan-xiong Ke, Xin-miao Liang *Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography. Journal of Chromatography A, 2009, 1216: 2136-2141,

[7] Xin-miao Liang *, Yu Jin, Yan-ping Wang, Gao-wa Jin, Qing Fu, Yuan-sheng Xiao,Quantitative and qualitative analysis in quality control of traditional Chinese medicines (review) Journal of Chromatography A, 2009,1216 : 2033-2034,

[8] Yu Jin, Xing-ya Xue, Fei-fang Zhang, Jin Zhang, Hui Shi, Yuan-sheng Xiao, Yan-xiong Ke, Xin-Miao Liang^*, Rapid prediction and optimization of concentration conditions for preparative fractions by solid-phase extraction. Journal of separation science, 2008, 31: 615 – 621.

[9] Yu Jin, Yuan-sheng Xiao, Fei-fang Zhang, Xing-ya Xue, Qing Xu, Xin-miao Liang ^*, Systematic screening and characterization of flavonoid glycosides in Carthamus tinctorius L. by liquid chromatography/UV diode-array detection/electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis, 2008, 46:418–430.

[10] Yu Jin, Xiu-li Zhang, Hui Shi, Yuan-sheng Xiao, Yan-xiong Ke, Xing-ya Xue, Fei-fang Zhang, Xin-miao Liang ^*, Characterization of C-glycosyl quinochalcones in Carthamus tinctorius L. by ultraperformance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry (UPLC/Q-TOF ) Rapid communication in mass spectrometry, 2008, 22: 1275–1287. 

[11] Zhi-mou Guo, Yu Jin, Tu Liang, Yan-fang Liu, Qing Xu, Xin-miao Liang, Aiwen Lei, Synthesis, chromatographic evaluation and hydrophilic interaction/reversed-phase mixed-mode behavior of a "Click beta-cyclodextrin" stationary phase, Journal of Chromatography A, 2009,1216, 257–263.

[12] Yong-ping Zhang, Yu Jin, Pei-chun Dai, Hui Yu, Dan-hua Yu, Yan-xiong Ke and Xin-miao Liang. Phenylene-bridged hybrid silica spheres for high performance liquid chromatography. Anal. Methods, 2009, 1, 123 - 127

[13] Hong-xue Huang, Yu Jin, Mei-yun Xue, Long Yu, Qing Fu, Yan-xiong Ke, Chang-hu Chu and Xin-miao Liang. A novel click chitooligosaccharide for hydrophilic interaction liquid chromatography. Chem. Comm. 2009,6973-6975

[14] Yan-ming Liu, Zhi-mou Guo, Yu Jin, Xing-ya Xue, Qing Xu, Fei-fang Zhang, Xin-miao Liang. "Click oligo(ethylene glycol)": An excellent orthogonal stationary phase to C18 for two-dimensional reversed-phase/reversed-phase liquid chromatography , Journal of Chromatography A, 2008, 1206: 153–159