須志平 博士 副教授 碩士生導(dǎo)師
電話：021-64253979
辦公室：實驗十八樓1310A室
E-mail： zhipingxu@ecust.edu.cn
個人簡介：
1998.09-2002.06 農(nóng)學(xué)學(xué)士 南京農(nóng)業(yè)大學(xué) 植物保護系
2002.09-2008.06 理學(xué)博士 南京農(nóng)業(yè)大學(xué) 植物保護學(xué)院 農(nóng)藥系
2008.07-至今 華東理工大學(xué) 藥學(xué)院 藥物化工研究所
2015.09-2016.10 訪問學(xué)者 美國 Kansas State University 昆蟲系
研究方向：
? 農(nóng)藥的生物評價及生理毒理研究：
1. 針對綠色化學(xué)農(nóng)藥的創(chuàng)制需求，建立多種靶標昆蟲的活體和離體篩選模型，進行生物活性評價、藥效分析和作用機制研究；
2. 借助細胞技術(shù)，利用昆蟲細胞系和急性解離昆蟲神經(jīng)細胞，對新殺蟲化合物和重要殺蟲劑品種進行細胞毒理學(xué)研究；
? 殺蟲劑毒理學(xué)和害蟲抗藥性研究：
構(gòu)建煙粉虱（CYP6CM1）和果蠅（CYP6G1）的細胞色素P450s體外表達系統(tǒng)，用于新型殺蟲化合物和重要殺蟲劑品種的代謝機理和交互抗性研究；
? RNAi技術(shù)在害蟲治理中的應(yīng)用:
納米滾環(huán)轉(zhuǎn)錄技術(shù)（RCT）在跳甲和鱗翅目害蟲RNAi中的應(yīng)用研究；
科研經(jīng)歷：
目前在領(lǐng)域內(nèi)相關(guān)學(xué)術(shù)期刊參與發(fā)表22篇SCI學(xué)術(shù)論文，其中以第一作者或通訊作者發(fā)表學(xué)術(shù)論文10篇。主持國家自然科學(xué)基金青年基金1項 （31501674），完成中央高校基本科研業(yè)務(wù)費專項基金和上海市優(yōu)秀青年教師基金各1項；先后參與農(nóng)藥領(lǐng)域國家重點研發(fā)計劃、973計劃、十二五國家科技支撐計劃以及上海市科技支撐重點項目。參與申請發(fā)明中國專利8項，PCT專利3項，中國專利授權(quán)3項，美國授權(quán)專利1項，加拿大授權(quán)專利1項。
招生專業(yè)：
1. 學(xué)術(shù)學(xué)位碩士招生專業(yè)
植物保護（090400）農(nóng)藥毒理學(xué)方向
2. 專業(yè)學(xué)位碩士招生專業(yè)
生物與醫(yī)藥（制藥工程0860）
發(fā)表部分論文：
[1] Zhiping Xu, Lianhua Zhu, Yun Yang, Yang Zhang, Miaoqing Lu, Liming Tao, Wenping Xu*. Bifenthrin induces DNA damage and autophagy in Spodoptera frugiperda Sf9 insect cells.In Vitro Cellular & Developmental Biology – Animal.2021, 57:264–271
[2] 吳嘉瑤, 梅倩倩, 吳勇超, 程家高*,李忠, 須志平*.新煙堿殺蟲劑環(huán)氧蟲啶對苜蓿蚜的毒力及其在苜蓿蚜和水稻中的降解轉(zhuǎn)化. 植物保護學(xué)報，2019，46（2）：401-408.
[3] Zhiping Xu , Shen Li , Yujun Shen, Meijun Chen, Xusheng Shao*.Spiropyran-azobenzene-DBU system as solvent indicator. Tetrahedron Letters.2018, 59, 3829–3832
[4] Zhiping Xu*, Zhenhong Gao, Xusheng Shao*. Light-triggered release of insecticidally active spirotetramat-eno. Chinese Chemical Letters. 2018, 29，1648–1650
[5] Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang Zhang,Yun Yang, Liming Tao*. Pyrethrum-extract induced autophagy in insect cells: A new target?Pestic Biochem Physiol. 2017,137: 21-26.
[6] 吳勇超, 須志平*, 邵旭升, 程家高*, 李忠. 環(huán)氧蟲啶對苜蓿蚜的毒力及對其體內(nèi)解毒酶活性的影響[J]. 農(nóng)藥學(xué)學(xué)報 2016, 18(6): 710-716.
[7] Ziqian Zhang, Jiayao Wu, Zhihao Shang, Chao Wang, Jiagao Cheng,Xuhong Qian, Yi Xiao,*Zhiping Xu,* and Youjun Yang*. Photocalibrated NO Release from N?Nitrosated Napthalimides upon One-Photon or Two-Photon Irradiation. Anal. Chem., 2016, 88, 7274-7280.
[8] Zhiping Xu, Lina Shi, Danping Jiang, Jiagao Cheng, Xusheng Shao*, Zhong Li. Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner. Scientific Reports, 2015, 5, 13962.
[9] Baoyan Zhang, Zhiping Xu*, Yixi Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Li Zhong. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells. Pestic Biochem Physiol. 2015, 119, 81-89.
[10] Xin Fang, Ying Tong Di, Yu Zhang, Zhi Ping Xu, Yang Lu, Qian Qian Chen, Qi Tai Zheng, and Xiao Jiang Hao*. Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforate. Angew. Chem. Int. Ed.2015, 54, 5592 –5595
[11] Ziqian Zhang, Baoyan Zhang, Xuhong Qian, Zhong Li, Zhiping Xu*, Youjun Yang*. Simultaneous Quantification of Hg2+ and MeHg+ in Aqueous Media with a Single Fluorescent Probe by Multiplexing in the Time Domain. Anal. Chem., 2014, 86, 11919-11924.
[12] Linlin Song, Zuhai Lei, Baoyan Zhang, Zhiping Xu*, Zhong Li* and Youjun Yang*. A Zero-Background Fluorescent Probe for Hg2+ Designed via the “Covalent-Assembly” Principle. Anal. Methods, 2014, 6, 7597–7600
[13] Siyuan Lu, Xusheng Shao, Zhong Li, Zhiping Xu*, Shishuai Zhao, Yinli Wu, and Xiaoyong Xu*. Design, Synthesis and Particular Biological Behaviors of Chain-opening Nitromethylene Neonicotinoids with cis-Configuration. J. Agric. Food Chem. 2012, 60(1), 322-330.
[14] Fengyi Liu§, Zhiping Xu§, Yu Cheng Zhu, Fangneng Huang, Yanhua Wang, Huiling Li, Hua Li, Congfen Gao, Weijun Zhou and Jinliang Shen*. Evidence of field-evolved resistance to Cry1Ac-expressing Bt cotton in Helicoverpa armigera (Lepidoptera: Noctuidae) in northern China. Pest Management Science, 2010, 66(2):155–161.
[15] Zhiping Xu, Fengyi Liu, Jin Chen，Fangneng Huang, David A Andow, Yanhua Wang, Yu Cheng Zhu and Jinliang Shen* . Using F2 screen to monitor frequency of resistance alleles to Bt cotton in field populations of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). Pest Management Science, 2009, 65:391-397.
[16] Fengyi Liu§, Zhiping Xu§, Juhua Chang, Jin Chen, Fenxia Meng, Yu Cheng Zhu, Jinliang Shen*. Resistance allele frequency to Bt cotton in field populations of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) in China. Journal of Economic Entomology,2008, 101(3): 933-943.
[17] Wang Yanhua, Gao Congfen, Xu Zhiping, Zhu Yu Chen, Lin Youwei, Dai Dejiang, Zhou Weijun, Shen Jinliang*. Buprofezin susceptibility survey, resistance selection and preliminary determination of resistance mechanism in Nilaparvata lugens (Homopetra: Delphacidae). Pest Management Science, 2008, 64(10):1050-1056.
[18] Yu Cheng Zhu, Fengyi Liu, Zhiping Xu, Juhua Chang, Jinliang Shen. F1 Screening for Resistance Gene Alleles to Bt Cotton in Helicoverpa armigera: How to Differentiate S and R Genotypes. J. Entomol. Sci. 2008. 43(3): 311-319.
